Mu Sigma Chapter of Sigma Gamma Rho Sorority, Incorporated was organized on December 8, 1945 by Southwest Region Syntaktes Mary Scales Carter of Houston, Texas with the assistance of sorors from New Orleans, Louisiana. Charter members of Mu Sigma are Mrs. Pansy Black, Mrs. Iceola W. Johnson, Mrs. Sarah Owens, Mrs. Mercedes Piper, Mrs. Della E. Sanders, Mrs. Evelyn G. Tilliston, Miss Edith B. Smith.

Soror Ellis was instrumental in gathering this outstanding group of women together to organize this great chapter. Soror Ellis, a transfer from Epsilon Sigma Chapter of New Orleans to Mu Sigma Chapter, was elected as the first Basileus.  Other Basilei of Mu Sigma include chronologically Sorors Sarah Owens, Viola Kent, A. O. Davis, Theresa M. Berryhill, Irma B. Poe, Earless Hope, Nellrose R. Jordan, Marion W. Jones, Catherine D. James, Johnita Scott, Sybil K. Thomas, Brenda J. Canty, Evelyn Jenkins, Brenda Smith, and Elaine Doyle. 

The Southwestern Syntaktes, along with sorors from Epsilon Sigma Chapter in New Orleans conducted the chartering ceremony. In conjuction with the organization of Mu Sigma Chapter, Beta Alpha Chapter was also organized on the campus of Southern University. Charter members of Beta Alpha Chapter are Sorors Gloria Bell, Rosebud Jontenberry, Julia Mae Rainey, Jessie Lee Smith and Georgia Mae Washington.

Over the last sixty-six years, Mu Sigma has continued to grow in membership and has made a notable positive impact on the Greater Baton Rouge community and specifically on adolescent and teen females. Being a strong promoter of education and high scholastic attainment, Mu Sigma awards annual scholarships to high school and college students on the local level. Mu Sigma has been instrumental in enhancing the social, cultural, educational and emotional well being of hundreds of young ladies in the area through its Rhoer and Debutante programs.

Additionally, implementation of the national programs of Sigma Gamma Rho Sorority–Project Reassurance, Mwanamugimu Essay Contest, Wee Savers, and Big Book Bag–and local programs serve to improve the quality of life for youth and others in the community. Mu Sigma supports other worthwhile initiatives through financial contributions to the local NAACP, Sickle Cell Anemia Foundation, March of Dimes, Women’s Council, National Council of Negro Women, St. Jude Research Hospital, and DeBose National Piano Competition Foundation.

Mu Sigma has sponsorship of three undergraduate chapters, Beta Alpha at Southern University, Gamma Pi at Louisiana State University, and Pi Iota at Southeastern University. To date, Mu Sigma has twenty-two life members–Irma Allen, Theresa M. Berryhill, Brenda Canty, Elouise Colbert, Deborah Daniels, Elaine Doyle, Dottie Francois, Ida Gardner, Dorothy Haysbert, Rochelle Howard, Jacqueline Hunt, Lillian Jackson, Evelyn Jenkins, Peggy London, Myrtle Moran, Carol Parker, Ruby Sanchez, Johnita Scott, Brenda Smith, Trudy Segars, Deirdre Harris Stepter and Sybil Dianne Thomas. On July 17, 2000, Mu Sigma held a groundbreaking ceremony to officially announce its plan to build a Mu Sigma house at 1738 Harding Boulevard, Baton Rouge, Louisiana.

Mu Sigma Chapter operates under the guidance of the Southwest Region Syntaktes of Sigma Gamma Rho Sorority, Inc. The chapter is located in Area V of the Southwest Region which is governed by the Regional Syntaktes, Brenda Canty, a member of Mu Sigma Chapter.